2-bromo-2-(2-fluorophenyl) -1-cyclopropylethanone
2-bromo-2-(2-fluorophenyl) -1-cyclopropylethanone
2-bromo-2- (2-fluorophenyl) -1-cyclopropylethanone inoshandiswa sepakati pePrasugrel.
Prasugrel ndeye thiophenopyridine antiplatelet yakagadzirwa naEli Lilly uye daiichisankyo, muJapan anogadzira mishonga.I precursor drug.Inoumba molecule inoshanda mushure memetabolism kuburikidza ne cytochrome P450 muchiropa uye inosanganiswa neplatelet P2Y12 receptor kuti iite inoshanda kurwisa platelet aggregation.Zvidzidzo zvekiriniki zvakaratidza kuti 60 mg dose ine zvirinani anticoagulant mhedzisiro pane 300 mg yakajairika dosi uye 600 mg yakawedzera dose ye clopidogrel, iyo inogona kuderedza yakazara njodzi yekurwiswa kwemoyo, sitiroko uye kufa nekuda kwechirwere chemoyo ne20%, uye inokurumidza kuita. , yakanaka yekurapa maitiro, yakanaka kurwisa zvinodhaka uye bioavailability, uye yakaderera chepfu.
JIN DUN Medical aneISO qualification uye inosangana neGMP yekugadzira zviyero, vakashandirwa mudzimba nevekunze nyanzvi dzekugadzira zvinodhaka vane ruzivo rwakapfuma kutungamira R&D yekambani.
TECHNOL OGY ADVANTAGES
●High Pressure Catalytic Hydrogenation .High Pressure Hydrogenolysis Reaction .Cryogenic Reaction (<-78%C)
●Aromatic Heterocyclic Synthesis
● Rearrangement Reaction
●Chiral Resolution
●Heck, Suzuki,Negishi,Sonogashira .Gignard Reaction
Equipments
Yedu Lab ine midziyo yakasiyana-siyana yekuedza uye yekuedza, yakadai se: NMR (Bruker 400M), HPLC, chiral-HPLC, LC-MS, LC-MS/MS (API 4000), IR, UV, GC, GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Differential Scanning Calorimeter (DSC), Electron Microscope...
R&D Chikwata
Jindun Medical ine boka revashandi veR&D nyanzvi, uye inoshandisa nyanzvi zhinji dzemumba nedzekunze dzekugadzira zvinodhaka kutungamira R&D, zvichiita kuti kubatanidza kwedu kuve kwakanyatso uye kushanda zvakanaka.
Isu takabatsira akati wandei epamusoro makambani emishonga emishonga, akadaiHansoh, Hengrui uye HEC Pharm.Pano ticharatidza chikamu chavo.
Customization Case One:
Cas Nha.: 110351-94-5
Customization Nyaya Yechipiri:
Cas Nha.: 144848-24-8
Customization Nyaya Yetatu:
Cas Nha.: 200636-54-0
1.Gadzirisa New Intermediates kana maAPI.Zvakangofanana nepamusoro pekugovanisa kesi, vatengi vane zvinodikanwa kune chaiwo maIntermediates kana APIs, uye havagone kuwana zvigadzirwa zvinodikanwa mumusika, saka isu tinogona kubatsira kuGadzirisa.
2.Process Optimization for Old Products.Chikwata chedu chichabatsira Kukwirisa nekuvandudza kugadzirwa kwakadai nzira yemaitiro yasakara, mutengo wekugadzira wakakwira, uye kushanda kwacho kwakadzikira.Tinogona kupa zvizere zvinyorwa zvekufambisa tekinoroji uye kuvandudzwa kwemaitiro, kubatsira mutengi kuti awedzere kugadzirwa.
Kubva pazvinangwa zvezvinodhaka kusvika kuINDs, JIN DUN Medical inokupa iweimwe-stop personalized R&D mhinduro.
JIN DUN Medical inoomerera pakugadzira timu ine zviroto, kugadzira zvigadzirwa zvine chiremera, zvine hungwaru, zvine hungwaru, uye kuenda zvese kunze kuti uve shamwari yakavimbika uye shamwari yevatengi!
![3'-Amino-2′-hydroxy-[1,1'-bipheny] -3-carboxylic acid](http://cdn.globalso.com/jindunchem-med/image351-300x300.png)
