4-Methoxybenzylalkohol;ANISALKOHOL;4-methoxy-benzenemethano;

Pakati peMoxonidine
Inogona kufadza pakati α2 receptors uye kukonzera antihypertensive mhedzisiro, yakafanana neclonidine.Muyero wekutora nemuromo (90%) uye bioavailability (88%) zvese zvakakwirira, uye hapana yekutanga-pass effect.Nhamba yepamusoro yeropa inoonekwa 1 kusvika maawa matatu mushure mekutora mushonga.Yakawanda yacho inobudiswa neitsvo.t1/2 inenge maawa maviri.Clinically inoshandiswa kune hypertension.

Mvura isina ruvara kana yero zvishoma.Iyo yakanyunguduka ndeye 23-25.5 ° C, iyo yekubikira i159 ° C, hukama hwehukama ndeye 1.113 (15/15 ° C), uye refractive index ndeye 1.5442.Zviri nyore kunyungudika mudoro uye ether, inenge isinganyungudike mumvura.

Ichi chigadzirwa chine kunhuhwirira kunotapira fennel uye chinowanzoshandiswa mukugadzirira kwejasmine, lilac nezvimwe zvinonaka, uye zvakakodzera kugadzirira kwezvinonhuwira.Ichi chigadzirwa chikafu chinodyiwa chinobvumidzwa nenyika yangu GB2760-86.Inonyanya kushandiswa kugadzira zvinonaka zvakaita sevanilla, chokoreti, cocoa, almond, uye peach.Inoshandiswawo mune organic synthesis uye se solvent.

Nokuderedza anisaldehyde.Cannizzaro inopindirana neanise, formaldehyde uye sodium hydroxide mu ethanol kugadzira p-methoxybenzyl doro.

Mushure mekunge ethanol yadzoserwa nedistillation, mafuta anowanikwa neanoita anotorwa nebenzene, acidified nekuwedzera acetic acid, uye yozogadziriswa nesodium bicarbonate kune isina simba alkaline.Mushure mekugeza nemvura kusvika pakusarerekera, benzene inodzoserwa nedistillation, uye inosara inoiswa muvacuum distillation kuti iwane p-methoxy Benzyl doro.

Inoshanda nekukurudzira pakati presynaptic α2-receptors.Iyo antihypertensive effect yakafanana neye calcium antagonist nifedipine uye ACE inhibitor captopril.Inoshandiswa kune yakakosha hypertension.