Unhu hwakanaka 99% 2-Cyanobenzyl Bromide;Alpha-Bromo-O-Toluonitrile CAS: 22115-41-9

Isu hatizoyedze zvatinokwanisa zvikuru kupa makambani emhando yepamusoro kumutengi wese, asi zvakare takagadzirira kugamuchira chero zano rinopihwa nevatengi vedu reGood quality 99% 2-Cyanobenzyl Bromide;Alpha-Bromo-O-Toluonitrile CAS: 22115-41-9, Chikwata chefemu yedu pamwe nekushandiswa kwematekinoroji ekucheka-cheka chinopa zvigadzirwa zvemhando yepamusoro zvinoyemurwa zvakanyanya uye zvinoyemurwa netarisiro yedu pasirese.
Isu hatizoyedze zvedu zvakanyanya kupa makambani akanakisa kune angangoita mutengi wese, asi zvakare takagadzirira kugamuchira chero zano rinopihwa nevatengi veduChina 2-Cyanobenzyl Bromide Powder uye Alpha-Bromo-O-Toluonitrile, Isu tinotenda zvakasimba kuti tekinoroji uye sevhisi ndiyo hwaro hwedu nhasi uye mhando ichagadzira madziro edu akavimbika emangwana.Isu chete tine zvirinani uye zvirinani mhando, taigona kuwana vatengi vedu uye isu pachedu, zvakare.Tikugashirei vatengi pese pashoko kuti tibatane nesu kuti tiwane rimwe bhizinesi uye hukama hwakavimbika.Tagara tiri pano tichishandira zvaunoda pese paunoda.

Shandisa:Pakati peLinagliptin.

Shandisa:Pakati peLinagliptin
Executive mwero:bhizinesi standard
Muedzo:98-102%

Kunze:Hupfu hwakachena kusvika kuyero
Package:25kg / chigubhu

Kuongorora iripo linagliptin uye kiyi yayo yepakati 8-bromo-7-(2-butynyl)-3,7-dihydro-3-methyl-1--[(4-methyl -2-quinazolinyl)methyl)-1H-purine- 2,6-dione (11) synthesis nzira, tsvaga nzira yekugadzira yakakodzera kugadzirwa kwemaindasitiri.Nzira: pfupikisa nzira dzakasiyana dzekugadzira.Migumisiro uye mhedziso: Nzira 2.2 ine maitiro akareruka uye mutengo wakaderera, uyo wakanyatsokodzera kugadzirwa kwemaindasitiri.

8-bromo-3,7-dihydro-3-methyl-1H-purine-2,6-dione ndiyo yakakosha yepakati mukugadzirwa kweiyo hypoglycemic drug linagliptin.Iyo synthesis ye1 inoshandisa methyl urea uye cyanoacetic acid sezvinhu zvekutanga, uye inosangana nenhanho-nhanho maitiro e condensation, cyclization, nitrosation, kuderedza, cyclization, uye bromine ine goho rakazara re46.3%.Izvo zvimiro zvevose vepakati zvakasimbiswa ne1HNMR.

Chigadzirwa chazvino chine chekuita neyakapusa nzira yekugadzirira yepamusoro-purity linagliptin.Quinazoline, kiyi yepakati pekugadzira poto ye linagliptin 8 bromo 7 (2 butyne 1 base) 3,7 dihydro 3 methyl 1 [(4 methyl 2 quinazolinyl) methyl] 1H Purine 2,6 dione, yepakati inoparadzaniswa ne kusefa, uyezve kuita ne (R) 3 aminopiperidine dihydrochloride kuwana mhinduro ine linagliptin.Mushure memhinduro ine linagliptin yagadziriswa zvakare, Deliraliptin yakachena chigadzirwa.Kugadzirira kwekiyi yepakati pechigadzirwa chiripo kunotora nzira yepoto imwe, iyo iri nyore kushanda uye inovandudza goho.Mushure mekunge kiyi yepakati yaparadzaniswa, inobatwa ne (R) 3 aminopiperidine dihydrochloride, nekudaro Kuwana yakakwirira-kuchena linagliptin inosanganawo nekugadzirwa uye kuziviswa zvinodiwa zvemakambani emishonga kusvika pamwero mukuru.

Isu hatizoyedze zvatinokwanisa zvikuru kupa makambani emhando yepamusoro kumutengi wese, asi zvakare takagadzirira kugamuchira chero zano rinopihwa nevatengi vedu reGood quality 99% 2-Cyanobenzyl Bromide;Alpha-Bromo-O-Toluonitrile CAS: 22115-41-9, Chikwata chefemu yedu pamwe nekushandiswa kwematekinoroji ekucheka-cheka chinopa zvigadzirwa zvemhando yepamusoro zvinoyemurwa zvakanyanya uye zvinoyemurwa netarisiro yedu pasirese.
Hunhu hwakanakaChina 2-Cyanobenzyl Bromide Powder uye Alpha-Bromo-O-Toluonitrile, Isu tinotenda zvakasimba kuti tekinoroji uye sevhisi ndiyo hwaro hwedu nhasi uye mhando ichagadzira madziro edu akavimbika emangwana.Isu chete tine zvirinani uye zvirinani mhando, taigona kuwana vatengi vedu uye isu pachedu, zvakare.Tikugashirei vatengi pese pashoko kuti tibatane nesu kuti tiwane rimwe bhizinesi uye hukama hwakavimbika.Tagara tiri pano tichishandira zvaunoda pese paunoda.