Rivaroxaban(S)-Rivaroxaban;BAY 59-7939;RivaroxabanIsomer;Rivaroxaban;
Rivaroxaban(S)-Rivaroxaban;BAY 59-7939;RivaroxabanIsomer;Rivaroxaban;
Inoshandiswa muvarwere vakuru vane kusarudzwa kwehudyu kana mabvi ekutsiva kuvhiyiwa kudzivirira venous thrombosis (VTE).
Inoshandiswa kudzivirira kana kuderedza kuumbwa kwethrombosis, deep vein thrombosis (DVT) uye pulmonary embolism (PE) mushure mekuvhiyiwa kwehudyu kana mabvi.
Nhamba yakakurudzirwa ndeyemuromo rivaroxaban 10mg, kamwe chete pazuva.Rivaroxaban 10mg inogona kutorwa nechikafu kana yoga.Rivaroxaban 15mg kana 20mg mapiritsi anofanira kutorwa nechikafu.
chiyero: usp40
Chiyero: 99-102%
Kunze: Hupfu chena
Package: 25kg / chigubhu
Tora 4-(4-aminophenyl) morpholin-3-one (SM-1), (S)-N-glycidyl phthalimide (SM-2), 5-chlorothiophene-2- Formyl chloride (SM-3) ndiyo yekutanga zvinhu. .Mushure mekugadzirisa, cyclization, aminolysis uye acylation, iyo isina kuchena rivaroxaban inowanikwa, uye yakapedzwa rivaroxaban inonatswa.
Kugadzirira: Ichi chigadzirwa chitsvuku chine firimu-yakavharwa piritsi.
Zvishandiso
Tablet core: microcrystalline cellulose, croscarmellose sodium, lactose monohydrate, hypromellose, sodium lauryl sulfate, magnesium stearate.
Kupfeka: polyethylene glycol, hypromellose, titanium dioxide, iron oxide tsvuku
Rivaroxaban inonyanya kusarudzwa, mushonga wemuromo unodzivisa zvakananga factor Xa.Kuburikidza nekusarudza zvakanyanya uye kukwikwidza kudziviswa kwemahara uye akasungwa factor Xa uye prothrombin chiitiko, wedzera iyo activated partial thromboplastin time plate (PT) uye prothrombin nguva (aPTT) nenzira inotsamira mudosi, iyo inogona kukanganisa coagulation mapopoma Iyo endogenous uye exogenous nzira. inhibisa kugadzirwa kwethrombin uye thrombosis.Rivaroxaban haidziviriri thrombin (activating factor Ⅱ), uye haina kuratidza kuti ine simba pamaplatelet.
Misiyano yakakosha pakati pe rivaroxaban uye fondaparinux/heparin ndeyokuti haidi kubatanidzwa kweantithrombin III uye inogona kupikisa zvakananga kusununguka uye kusungwa chinhu Xa;nepo heparin inoda antithrombin III kuti ishande, uye Iyo haina mhedzisiro pachinhu Xa mu prothrombin yakaoma.
JIN DUN Medical aneISO qualification uye inosangana neGMP yekugadzira zviyero, vakashandirwa mudzimba nevekunze nyanzvi dzekugadzira zvinodhaka vane ruzivo rwakapfuma kutungamira R&D yekambani.
TECHNOL OGY ADVANTAGES
●High Pressure Catalytic Hydrogenation .High Pressure Hydrogenolysis Reaction .Cryogenic Reaction (<-78%C)
●Aromatic Heterocyclic Synthesis
● Rearrangement Reaction
●Chiral Resolution
●Heck, Suzuki,Negishi,Sonogashira .Gignard Reaction
Equipments
Yedu Lab ine midziyo yakasiyana-siyana yekuedza uye yekuedza, yakadai se: NMR (Bruker 400M), HPLC, chiral-HPLC, LC-MS, LC-MS/MS (API 4000), IR, UV, GC, GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Differential Scanning Calorimeter (DSC), Electron Microscope...
R&D Chikwata
Jindun Medical ine boka revashandi veR&D nyanzvi, uye inoshandisa nyanzvi zhinji dzemumba nedzekunze dzekugadzira zvinodhaka kutungamira R&D, zvichiita kuti kubatanidza kwedu kuve kwakanyatso uye kushanda zvakanaka.
Isu takabatsira akati wandei epamusoro makambani emishonga emishonga, akadaiHansoh, Hengrui uye HEC Pharm.Pano ticharatidza chikamu chavo.
Customization Case One:
Cas Nha.: 110351-94-5
Customization Nyaya Yechipiri:
Cas Nha.: 144848-24-8
Customization Nyaya Yetatu:
Cas Nha.: 200636-54-0
1.Gadzirisa New Intermediates kana maAPI.Zvakangofanana nepamusoro pekugovanisa kesi, vatengi vane zvinodikanwa kune chaiwo maIntermediates kana APIs, uye havagone kuwana zvigadzirwa zvinodikanwa mumusika, saka isu tinogona kubatsira kuGadzirisa.
2.Process Optimization for Old Products.Chikwata chedu chichabatsira Kukwirisa nekuvandudza kugadzirwa kwakadai nzira yemaitiro yasakara, mutengo wekugadzira wakakwira, uye kushanda kwacho kwakadzikira.Tinogona kupa zvizere zvinyorwa zvekufambisa tekinoroji uye kuvandudzwa kwemaitiro, kubatsira mutengi kuti awedzere kugadzirwa.
Kubva pazvinangwa zvezvinodhaka kusvika kuINDs, JIN DUN Medical inokupa iweimwe-stop personalized R&D mhinduro.
JIN DUN Medical inoomerera pakugadzira timu ine zviroto, kugadzira zvigadzirwa zvine chiremera, zvine hungwaru, zvine hungwaru, uye kuenda zvese kunze kuti uve shamwari yakavimbika uye shamwari yevatengi!
![Casp ungin Acetate;Caspofungin acetate;Cancidas;Caspofungin acetate [USAN:BAN:JAN];](http://cdn.globalso.com/jindunchem-med/fbe17385-300x300.jpg)