Wholesale Hot Selling Ibrutinib Intermediates N-3 CAS 330792-70-6

Tichifunga nezve motto iyi, isu tave pakati pevanonyanya kugadzira tekinoroji, inodhura-inoshanda, uye inokwikwidza mutengo vagadziri ve Wholesale Hot Selling Ibrutinib Intermediates N-3 CAS 330792-70-6, Isu tinotarisira kukupa zvigadzirwa zvedu munguva pfupi iri kutevera, uye iwe uchaona quotation yedu ine musoro uye mhando yezvigadzirwa zvedu yakanaka kwazvo!
Tichifunga nezve motto iyi, isu tave pakati pevanonyanya kugadzira tekinoroji, inodhura-inoshanda, uye inokwikwidza mutengo vagadziriChina Ibrutinib N-3 uye Intermediates, Kusvika pari zvino zvigadzirwa zvedu zvakatengeswa kumabvazuva kweEurope, Middle East, Southeast, Africa neSouth America etc. Tine 13years nyanzvi yekutengesa uye kutenga muIsuzu zvikamu kumba nekune dzimwe nyika uye varidzi vemazuva ano emagetsi Isuzu zvikamu zvekuongorora masisitimu.Isu tinokudza mukuru wedu mukuru weKuvimbika mubhizinesi, kukoshesa musevhisi uye tichaita zvatinogona kupa vatengi vedu zvigadzirwa zvemhando yepamusoro uye sevhisi yakanaka.

Pakati peiyo synthesis yeallopurinol.

Iyo ndeimwe ye3-amino-4-inotsiva pyrazole akatevedzana.Inogona kushandiswa sepakati pekugadzira mishonga yakawanda yemishonga inobudirira, yakadai seallopurinol, imwe yepyrazolopyrimidine derivatives series, iyo yekupedzisira kubvira 1963 Kubva pakushandiswa kwayo kwekliniki, ndiyo yave iri mushonga mukuru wekurapa gout.Parizvino, kune nzira shoma dzinozivikanwa dzekugadzira

3-aminopyrazole-4-carboxamide hemisulfate muChina, kunyanya nekuita malononitrile uye triethyl orthoformate kugadzirira ethoxymethylene malononitrile, uyezve neThe reaction ye hydrazine hydrate inobereka 3-amino-4-cyanopyrazole, iyo inozopedzisira yaitwa ne concentrated acid kuti ibudise sulfuric acid.

3-aminopyrazole-4-carboxamide hemisulfate (Chen Huiru, Xiao Guomin et al. 3-aminopyrazole- Synthesis of 4-formamide hemisulfate [J]. Chemical Industry Times, 2008, 6 (22): 39 40), goho rose re synthesis nenzira iyi inenge 60% (yakaverengwa semalononitrile), nzira iyi Inosanganisira maitiro matatu-nhanho, matanho akareba, uye reagents inoshandiswa, yakadai semalononitrile uye ethoxymethylene malononitrile, inowedzera chepfu uye inodhura.Mukuwedzera, iyo 3-aminopyrazole-4 yakagadzirirwa nenzira iyi -Formamide hemisulfate ine ruvara rwakaoma kubvisa uye inoda kushandiswa kwekuwedzera, iyo inonyanya kuoma.

Kune mishumo mumabhuku ekunze anoshandisa pyridylamide hydrazone uye ethoxymethylene malononitrile seyakagadzirwa kuti iwane 3-amino-4-cyanopyrazole nekuwedzera uye cyclization, uye wobva waita neconcentrated sulfuric acid kuti uwane iyo yakanangwa compound (Reuken G Jones. activemethylene compounds [J] J Am Chem Soc. 1952,74(5) :4889 4891).Iyo mikuru yemidziyo inoshandiswa mune iyi nzira inodhura, maitiro ekuita goho haana kukwirira, uye purofiti yekugadzirwa kwemaindasitiri yakaderera.Zvinofanira kunge zvakaoma.

Executive standard:Enterprise Standard
Kunze:Off-white kana yellow powder

Package:25kg / chigubhu
assay (HPLC) zviri mukati Yakakura kupfuura kana kuenzana ne98.0%
kuchena (HPLC) zviri mukati Yakakura kupfuura kana kuenzana ne99.5%

JIN DUN Medical aneISO qualification uye inosangana neGMP yekugadzira zviyero, vakashandirwa mudzimba nevekunze nyanzvi dzekugadzira zvinodhaka vane ruzivo rwakapfuma kutungamira R&D yekambani.

TECHNOL OGY ADVANTAGES
●High Pressure Catalytic Hydrogenation .High Pressure Hydrogenolysis Reaction .Cryogenic Reaction (<-78%C)
●Aromatic Heterocyclic Synthesis
● Rearrangement Reaction
●Chiral Resolution
●Heck, Suzuki,Negishi,Sonogashira .Gignard Reaction

Equipments

Yedu Lab ine midziyo yakasiyana-siyana yekuedza uye yekuedza, yakadai se: NMR (Bruker 400M), HPLC, chiral-HPLC, LC-MS, LC-MS/MS (API 4000), IR, UV, GC, GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Differential Scanning Calorimeter (DSC), Electron Microscope…

R&D Chikwata

Jindun Medical ine boka revashandi veR&D nyanzvi, uye inoshandisa nyanzvi zhinji dzemumba nedzekunze dzekugadzira zvinodhaka kutungamira R&D, zvichiita kuti kubatanidza kwedu kuve kwakanyatso uye kushanda zvakanaka.

Isu takabatsira akati wandei epamusoro makambani emishonga emishonga, akadaiHansoh, Hengrui uye HEC Pharm.Pano ticharatidza chikamu chavo.

Customization Case One:

Cas Nha.: 110351-94-5

Customization Nyaya Yechipiri:

Cas Nha.: 144848-24-8

Customization Nyaya Yetatu:

Cas Nha.: 200636-54-0

1.Gadzirisa New Intermediates kana maAPI.Zvakangofanana nepamusoro pekugovanisa kesi, vatengi vane zvinodikanwa kune chaiwo maIntermediates kana APIs, uye havagone kuwana zvigadzirwa zvinodikanwa mumusika, saka isu tinogona kubatsira kuGadzirisa.

2.Process Optimization for Old Products.Chikwata chedu chichabatsira Kukwirisa nekuvandudza kugadzirwa kwakadai nzira yemaitiro yasakara, mutengo wekugadzira wakakwira, uye kushanda kwacho kwakadzikira.Tinogona kupa zvizere zvinyorwa zvekufambisa tekinoroji uye kuvandudzwa kwemaitiro, kubatsira mutengi kuti awedzere kugadzirwa.

Kubva pazvinangwa zvezvinodhaka kusvika kuINDs, JIN DUN Medical inokupa iweimwe-stop personalized R&D mhinduro.

JIN DUN Medical inoomerera pakugadzira timu ine zviroto, kugadzira zvigadzirwa zvine chiremera, zvine hungwaru, zvine hungwaru, uye kuenda zvese kunze kuti uve shamwari yakavimbika uye shamwari yevatengi!

Tichifunga nezve motto iyi, isu tave pakati pevanonyanya kugadzira tekinoroji, inodhura-inoshanda, uye inokwikwidza mutengo vagadziri ve Wholesale Hot Selling Ibrutinib Intermediates N-3 CAS 330792-70-6, Isu tinotarisira kukupa zvigadzirwa zvedu munguva pfupi iri kutevera, uye iwe uchaona quotation yedu ine musoro uye mhando yezvigadzirwa zvedu yakanaka kwazvo!
WholesaleChina Ibrutinib N-3 uye Intermediates, Kusvika pari zvino zvigadzirwa zvedu zvakatengeswa kumabvazuva kweEurope, Middle East, Southeast, Africa neSouth America etc. Tine 13years nyanzvi yekutengesa uye kutenga muIsuzu zvikamu kumba nekune dzimwe nyika uye varidzi vemazuva ano emagetsi Isuzu zvikamu zvekuongorora masisitimu.Isu tinokudza mukuru wedu mukuru weKuvimbika mubhizinesi, kukoshesa musevhisi uye tichaita zvatinogona kupa vatengi vedu zvigadzirwa zvemhando yepamusoro uye sevhisi yakanaka.